Product Name :
3,4-Dihydroxybenzaldehyde (CAS 139-85-5)
Synonym :
Protocatechuic aldehyde
Application :
3,4-Dihydroxybenzaldehyde is an apoptosis inducer of human leukemia cells
CAS:
139-85-5
Purity:
≥98%
Molecular Weight:
138.12
Formula :
C7H6O3
Physical state:
Solid
solubility :
Soluble in water (50 g/l), ethanol (790 g/l), methanol, and ether.
Shipping Condition :
Store at 4° C
Melting point:
150-159° C
SMILES:
OC1=CC=C(C=O)C=C1O
References:
:Mechanistic study of electrochemical oxidation of 2,5-dihydroxybenzoic acid and 3,4-dihydroxybenzaldehyde in the presence of 3-hydroxy-1H-phenalene-1-one. | Nematollahi, D. and Amani, A. 2008. Chem Pharm Bull (Tokyo). 56: 513-7. PMID: 183791003,4-dihydroxybenzaldehyde purified from the barley seeds (Hordeum vulgare) inhibits oxidative DNA damage and apoptosis via its antioxidant activity. | Jeong, JB., et al. 2009. Phytomedicine. 16: 85-94. PMID: 19022639Apoptotic cell death through inhibition of protein kinase CKII activity by 3,4-dihydroxybenzaldehyde purified from Xanthium strumarium. | Lee, BH., et al. 2008. Nat Prod Res. 22: 1441-50. PMID: 190238073,4-Dihydroxybenzaldehyde Derived from Prunus mume Seed Inhibits Oxidative Stress and Enhances Estradiol Secretion in Human Ovarian Granulosa Tumor Cells. | Kono, R.81190-89-8 custom synthesis , et al. 2014. Acta Histochem Cytochem. 47: 103-12. PMID: 25320407A chemical model of catechol-O-methyltransferase. Methylation of 3,4-dihydroxybenzaldehyde in aqueous solution. | Sugata, S., et al. 1989. Chem Pharm Bull (Tokyo). 37: 1143-6. PMID: 26300853,4-Dihydroxybenzaldehyde quenches ROS and RNS and protects human blood cells from Cr(VI)-induced cytotoxicity and genotoxicity.869718-81-0 Description | Husain, N. and Mahmood, R. 2018. Toxicol In Vitro. 50: 293-304. PMID: 29665407Anti-corrosion and microstructural properties of Ni-W alloy coatings: effect of 3,4-Dihydroxybenzaldehyde. | Pramod Kumar, U., et al. 2019. Heliyon. 5: e01288. PMID: 30899827Anti-neuroinflammatory effect of 3,4-dihydroxybenzaldehyde in ischemic stroke. | Li, X., et al. 2020. Int Immunopharmacol. 82: 106353. PMID: 321430073,4-Dihydroxybenzaldehyde attenuates pentachlorophenol-induced cytotoxicity, DNA damage and collapse of mitochondrial membrane potential in isolated human blood cells. | Maheshwari, N. and Mahmood, R. 2022. Drug Chem Toxicol.PMID:33438527 45: 1225-1242. PMID: 32854525Cross-Linking Porcine Pericardium by 3,4-Dihydroxybenzaldehyde: A Novel Method to Improve the Biocompatibility of Bioprosthetic Valve. | Wu, B., et al. 2021. Biomacromolecules. 22: 823-836. PMID: 333757813,4-Dihydroxybenzaldehyde mitigates fluoride-induced cytotoxicity and oxidative damage in human RBC. | Anjum, R., et al. 2022. J Trace Elem Med Biol. 69: 126888. PMID: 34773916Anti-Allergic Effect of 3,4-Dihydroxybenzaldehyde Isolated from Polysiphonia morrowii in IgE/BSA-Stimulated Mast Cells and a Passive Cutaneous Anaphylaxis Mouse Model. | Kim, EA., et al. 2022. Mar Drugs. 20: PMID: 35200662Metabolomic analysis and pharmacological validation of the cerebral protective effect of 3,4dihydroxybenzaldehyde on cerebral ischemiareperfusion injury. | Luo, Y., et al. 2023. Mol Med Rep. 27: PMID: 36367170