Product Name :
3-formylrifamycin SV (CAS 13292-22-3)

Synonym :
3-Formylrifamycin

Application :
3-formylrifamycin SV is a compound that interacts with biological membranes

CAS:
13292-22-3

Purity:
≥98%

Molecular Weight:
725.78

Formula :
C38H47NO13

Physical state:
Solid

solubility :
Soluble in chloroform, and methanol.

Shipping Condition :
Store at room temperature

Melting point:
182-184° C

SMILES:
C[C@H]1/C=C/C=C(\\C(=O)NC2=C(C(=C3C(=C2O)C(=C(C4=C3C(=O)[C@](O4)(O/C=C/[C@@H]([C@H]([C@H]([C@@H]([C@@H]([C@@H]([C@H]1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)C=O)/C

References:
:Evaluation of the recently reported USP gradient HPLC method for analysis of anti-tuberculosis drugs for its ability to resolve degradation products of rifampicin. | Mohan, B., et al. 2003. J Pharm Biomed Anal. 31: 607-12. PMID: 12615251Polymer-supported (2,6-dichloro- 4-alkoxyphenyl)(2,4-dichlorophenyl)methanol: a new linker for solid-phase organic synthesis. | Kurosu, M., et al. 2007. Org Lett. 9: 1141-4. PMID: 17311394HPLC determination of rifampicin and related compounds in pharmaceuticals using monolithic column. | Liu, J., et al. 2008. J Pharm Biomed Anal. 46: 405-9. PMID: 18055155The behavior of PLGA microspheres containing rifampicin in alveolar macrophages. | Onoshita, T., et al. 2010. Colloids Surf B Biointerfaces. 76: 151-7. PMID: 19954935Lessons from seven decades of antituberculosis drug discovery. | Barry, CE. 2011. Curr Top Med Chem. 11: 1216-25. PMID: 2140150913C and 15N CP/MAS, 1H-15N SCT CP/MAS and FTIR spectroscopy as tools for qualitative detection of the presence of zwitterionic and non-ionic forms of ansa-macrolide 3-formylrifamycin SV and its derivatives in solid state.1885-46-7 Formula | Przybylski, P.121816-84-0 custom synthesis , et al. 2014. Magn Reson Chem. 52: 10-21. PMID: 24347399Structure and evaluation of antibacterial and antitubercular properties of new basic and heterocyclic 3-formylrifamycin SV derivatives obtained via ′click chemistry′ approach.PMID:33594904 | Pyta, K., et al. 2014. Eur J Med Chem. 84: 651-76. PMID: 25063947Pharmaceutical Development of Nanostructured Vesicular Hydrogel Formulations of Rifampicin for Wound Healing. | Wallenwein, CM., et al. 2022. Int J Mol Sci. 23: PMID: 36555855Development and Characterization of Pharmaceutical Systems Containing Rifampicin. | Dan Córdoba, AV., et al. 2023. Pharmaceutics. 15: PMID: 36678827The reaction of 3-formylrifamycin SV with sulphonium and phosphonium ylides. | Cricchio, R., et al. 1974. Farmaco Sci. 29: 358-65. PMID: 4838292High-pressure liquid chromatographic quantitation of rifampin and its two major metabolites in urine and serum. | Weber, A., et al. 1983. Rev Infect Dis. 5 Suppl 3: S433-9. PMID: 6635434Inactivated products of rifampicin by pathogenic Nocardia spp.: structures of glycosylated and phosphorylated metabolites of rifampicin and 3-formylrifamycin SV. | Morisaki, N., et al. 1993. J Antibiot (Tokyo). 46: 1605-10. PMID: 8244890Effect of rifampicin derivatives on the ion compartmentation of biological membranes. | Inouye, B., et al. 1977. J Antibiot (Tokyo). 30: 494-9. PMID: 885810